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| Year | Result |
| 2023 | Nolensville National (Tennessee) 4, Lake Mary (Florida) 1 |
| 2022 | Nolensville (Tennessee) 5, Loudoun South American (South Riding, Virginia) 2 |
| 2021 | Nolensville (Tennessee) 10, Martin County North (Palm City, Florida) 3 |
| 2020 | International tournament not held due to Covid-19 pandemic |
| 2019 | Loudoun South American (South Riding, Virginia) 12, Peachtree City National (Georgia) 2 (6 innings) |
| 2018 | Peachtree City American (Georgia) 3, Loudoun South American (South Riding, Virginia) 0 |
| 2017 | Greenville - North State (North Carolina) 8, Peachtree City National (Georgia) 6 |
| 2016 | Goodlettsville Baseball (Tennessee) 15, Peachtree City American (Georgia) 3 (4 innings) |
| 2015 | Northwood (Taylors, South Carolina) 7, Mechanicsville National (Virginia) 0 |
| 2014 | South Nashville (Tennessee) 9, Tuckahoe American (Henrico, Virginia) 4 |
| 2013 | South Nashville (Tennessee) 5, Tuckahoe American (Henrico, Virginia) 3 |
| 2012 | Goodlettsville Baseball (Tennessee) 1, Warner Robins American West (Georgia) 0 |
| 2011 | Warner Robins American East (Georgia) 4, New Tampa (Tampa, Florida) 2 |
| 2010 | Columbus Northern (Georgia) 9, Viera/Suntree (Melbourne, Florida) 2 |
| 2009 | Warner Robins American (Georgia) 6, Chantilly American (Virginia) 3 |
| 2008 | Citrus Park (Tampa, Florida) 11, Mobile Westside (Alabama) 0 (5 innings) |
| 2007 | Warner Robins American (Georgia) 10, Mobile Westside (Alabama) 9 |
| 2006 | Columbus Northern (Georgia) 5, Greater Dunedin (Florida) 0 |
| 2005 | Maitland (Florida) 3, Buckhead (Atlanta, Georgia) 1 |
| 2004 | Morganton (North Carolina) 7, Columbus Northern (Georgia) 4 |
| 2003 | East Boynton Beach (Florida) 4, Buckhead (Atlanta, Georgia) 0 |
| 2002 | Southwest Forsyth (Clemmons, North Carolina) 4, Bridgewater Community (Virginia) 2 |
| 2001 | Apopka National (Florida) 8, Sandy Springs (Georgia) 3 |
Southern Region Tournament (1957-2000)
| Year | Result |
| 2000 | Bellaire (Texas) 10, Barboursville (West Virginia) 0 (5 innings) |
| 1999 | Phenix City National (Alabama) 3, Kernersville (North Carolina) 2 |
| 1998 | Greenville - Tar Heel (Greenville, North Carolina) 6, Morristown American (Tennessee) 0 (4 innings; lightning) |
| 1997 | Manatee East (Bradenton, Florida) 3, College Station National (Texas) 2 (10 innings) |
| 1996 | R.L. Turner (Panama City, Florida) 7, Greenville - Tar Heel (Greenville, North Carolina) 1 |
| 1995 | Northwest 45 National (Spring, Texas) 3, Mint Hill (North Carolina) 0 |
| 1994 | Central Springfield (Virginia) 8, Northside (Tampa, Florida) 3 |
| 1993 | Tuckahoe American (Henrico, Virginia) 6, Sandy Plains (Georgia) 1 |
| 1992 | South Lake Charles (Louisiana) 8, Sagemont-Beverly Hills (Houston, Texas) 1 |
| 1991 | Dunedin National (Florida) 6, Mid-City (Lake Charles, Louisiana) 3 |
| 1990 | Cottage Hill (Mobile, Alabama) 3, Dunedin American (Florida) 2 (7 innings) |
| 1989 | Northside (Tampa, Florida) 8, Northwood (Taylors, South Carolina) 4 |
| 1988 | Northwest 45 (Spring, Texas) 3, Jeffersontown (Kentucky) 0 |
| 1987 | Morristown American (Tennessee) 8, Sarasota National (Florida) 7 (7 innings) |
| 1986 | Sarasota American (Florida) 16, Columbus Eastern (Georgia) 3 |
| 1985 | Morristown American (Tennessee) 2, Sarasota American (Florida) 1 |
| 1984 | Altamonte Springs National (Florida) 19, Huntsville Northern (Alabama) 6 |
| 1983 | East Marietta National (Georgia) 5, Vienna American (Virginia) 4 |
| 1982 | Sarasota National (Florida) 12, South Lexington (Kentucky) 2 |
| 1981 | Belmont Heights (Tampa, Florida) 6, Southwest Forsyth (Clemmons, North Carolina) 0 |
| 1980 | Belmont Heights (Tampa, Florida) 2, Clarksville National (Tennessee) 0 |
| 1979 | Burns Park (North Little Rock, Arkansas) 3, Mid-City (Lake Charles, Louisiana) 1 |
| 1978 | South Lexington (Kentucky) 5, Lake Jackson National (Texas) 1 |
| 1977 | Hub City (Hattiesburg, Mississippi) 1, Belmont Heights (Tampa, Florida) 0 |
| 1976 | Tuckahoe National (Henrico, Virginia) 12, Johnson City National (Tennessee) 6 |
| 1975 | Belmont Heights (Tampa, Florida) 4, Mint Hill (North Carolina) 3 |
| 1974 | Jackson American (Tennessee) 1, LaGrange (Texas) 0 |
| 1973 | Belmont Heights (Tampa, Florida) 7, Anderson (South Carolina) 3 |
| 1972 | Vienna National (Virginia) 4, Owensboro Southern (Kentucky) 0 |
| 1971 | Gardenside (Lexington, Kentucky) 2, Shaw Air Force Base (Sumter, South Carolina) 0 |
| 1970 | Nashville National Optimist (Tennessee) 7, East Marietta National (Georgia) 3 |
| 1969 | West Tampa (Florida) 1, Charleston Eastern (West Virginia) 0 (7 innings) |
| 1968 | Tuckahoe National (Henrico, Virginia) 3, Donelson National (Hermitage, Tennessee) 0 |
| 1967 | West Tampa (Florida) 3, St. Albans Eastern (West Virginia) 0 |
| 1966 | Westbury American (Houston, Texas) 3, Annandale-North Springfield National (Virginia) 0 |
| 1965 | Waco Northern (Texas) 4, Glenwood Hills American (Decatur, Georgia) 2 |
| 1964 | Brookly (Mobile, Alabama) 13, Edgewood American (Houston, Texas) 1 |
| 1963 | North Houston National (Texas) 6, Ashland American (Kentucky) 3 |
| 1962 | Val Verde County (Del Rio, Texas) 3, Mid-City (Lake Charles, Louisiana) 0 |
| 1961 | El Campo (Texas) 3, C. Dilworth Rotary (Charlotte, North Carolina) 0 |
| 1960 | Northeast Optimists (Fort Worth, Texas) 5, Biloxi American (Mississippi) 1 |
| 1959 | Gadsden National (Alabama) 5, Henderson National (Kentucky) 0 |
| 1958 | Gadsden National (Alabama) 7, Princess Anne (Lynnhaven, Virginia) 0 |
| 1957 | Monterrey Industrial (Monterrey, Mexico) 3, Owensboro Eastern (Kentucky) 0 |